The Epidermal Growth Factor Receptor (egfr) Pathway in Cancer Part Ii — Target Cancer Indications

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COPYRIGHT © 2007 NEW MEDICINE INC. UNAUTHORIZED PHOTOCOPYING, DISTRIBUTION OR ELECTRONIC STORAGE IS PROHIBITED BY LAW. THE EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) PATHWAY IN CANCER PART II — TARGET CANCER INDICATIONS AND TARGETING APPROACHES ERBB RECEPTORS ASSOCIATION BY CANCER INDICATION 1958 EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) 1959 Colorectal Cancer 1959 Head and Neck Cancer 1960 Lung Cancer 1960 Prostate Cancer 1961 Ovarian Cancer 1961 Brain Cancer 1961 Breast Cancer 1961 Pancreatic Cancer 1961 HER2/NEU (HER2, ERBB2) 1961 Breast Cancer 1961 Ovarian Cancer 1962 Pancreatic Cancer 1963 Osteosarcoma 1963 Lung Cancer 1963 Other Malignancies 1963 HER3 (ERBB3) 1964 HER4 (ERBB4) 1965 EGFRVARIANT III (EGFRVIII) 1965 TARGETING ERBB RECEPTORS FOR THE TREATMENT OF CANCER 1965 INTRACELLULAR TARGETING 1965 Reversible and Irreversible Inhibitors 1972 Specific, Dual, and Pan-ErbB Inhibitors 1973 EXTRACELLULAR TARGETING 1973 Naked Monoclonal Antibodies (MAb) 1973 Bispecific MAb 1980 Immunoconjugates 1980 IMMUNOTHERAPIES/VACCINES USING ERBB AS ANTIGENS 1980 MECHANISMS OF RESISTANCE AND TOXICITY 1981 RESISTANCE 1981 TOXICITY 1984

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تاریخ انتشار 2007